Hepatitis A is an acute infectious disease of the liver caused by the hepatitis A virus (HAV), an RNA virus, usually spread the fecal-oral route, transmitted person to person, by ingestion of contaminated food or water or through direct contact with an infectious person. HAV only causes acute hepatitis and is not associated with chronic liver disease. Most individuals infected with HAV develop non-specific constitutional signs and symptoms followed by gastrointestinal symptoms. Symptoms include fever, malaise, anorexia, nausea, abdominal discomfort, dark urine and jaundice. The disease course typically lasts less than 2 months. In rare cases, HAV can cause severe cases of fulminant hepatitis with fatal outcomes in otherwise healthy adults.
AmpliSens® HAV-FRT PCR kit is One-Step RT-PCR test for the qualitative detection of Hepatitis A virus RNA in clinical material (blood plasma, feces) and environmental objects (water samples). Kit contains Internal Control in order to check the extraction and reverse transcription process of individual sample and to identify possible reaction inhibition.