Hepatitis G virus

GB virus C (GBV-C), formerly known as Hepatitis G is a newly discovered form of liver inflammation caused by hepatitis G virus (HGV) from Flaviviridae family, a distant relative of the hepatitis C virus. Little is known about the frequency of HGV infection, the nature of the illness, but it is known is that transfused blood containing HGV has caused some cases of hepatitis. For this reason, patients with hemophilia and other bleeding conditions who require large amounts of blood or blood products are at risk of hepatitis G. Also at risk are patients with kidney disease who have blood exchange by hemodialysis, and those who inject drugs into their veins. Sexual transmission is possibile, but also infected mother can pass on the virus to her newborn infant. HGV virus has not yet been assigned to a genus, is not known to cause human disease. There have been reports that HIV patients coinfected with GBV-C can survive longer than those without GBV-C, but the patients may differ from each other in other ways. There is current active research into the virus' effects on the immune system in patients coinfected with GBV-C and HIV.

Often patients with hepatitis G are infected at the same time by the hepatitis B or C virus, or both. In about three of every thousand patients with acute viral hepatitis, HGV is the only virus present. There is some indication that patients with hepatitis G may continue to carry the virus in their blood for many years and so might be a source of infection for others.

HGV PCR kit is qualitative test for detection of HGV in the clinical samples. Real-Time PCR kit contains Internal Control that allows to check complete detection process – RNA Extraction, reverse transcription and amplification.

For detection, 2 channels – FAM/Green and JOE/HEX/ Yellow are needed.


New CE
mark
Type Pack Cat. No. Name Description Kit
format
No. of
tests
 CE Real Time RT+PCRR-V2-50-F(RG,iQ,Mx,Dt)-CEHGV-FRT
PDF
HGV One-Step RT-PCR kitNon-aliquoted55
Real TimeFEP KitsElectrophoresis KitsAla 1/4 Detector